56 Results for "

Melicope triphylla (Lam.) Merr.

" in MedChemExpress (MCE) Product Catalog:
Products (56)

56 Results for "Melicope triphylla (Lam.) Merr." in MCE Product Catalog:

44
Apilimod
Apilimod
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44 Publications Verification
Cat. No.: HY-14644
CAS No.: 541550-19-0
Purity:  99.80%
Synonyms: STA 5326; LAM-002A free base; AIT-101
Target:  

Interleukin Related PIKfyve

연구분야:  

Inflammation/Immunology Cancer

Apilimod (STA 5326) is a potent IL-12/IL-23 inhibitor, and strongly inhibits IL-12 with IC50s of 1 nM and 2 nM, in IFN-γ/SAC-stimulated human PBMCs and SAC-treated monkey PBMCs, respectively . Apilimod is a potent and highly selective PIKfyve inhibitor.
44
Apilimod mesylate
Apilimod mesylate
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44 Publications Verification
Cat. No.: HY-14644A
CAS No.: 870087-36-8
Purity:  99.83%
Synonyms: STA 5326 mesylate; LAM-002A; AIT-101 mesylate
Target:  

Interleukin Related PIKfyve

연구분야:  

Inflammation/Immunology Cancer

Apilimod (STA 5326) mesylate is a potent IL-12/IL-23 inhibitor, and strongly inhibits IL-12 with IC50s of 1 nM and 2 nM, in IFN-γ/SAC-stimulated human PBMCs and SAC-treated monkey PBMCs, respectively . Apilimod is a potent and highly selective PIKfyve inhibitor.
10
Fexaramine
Fexaramine
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10 Cited Publications
Cat. No.: HY-10912
CAS No.: 574013-66-4
Purity:  99.24%
Target:  

FXR Autophagy

연구분야:  

Others

Fexaramine is a potent and selective FXR agonist with an EC50 of 25 nM. Fexaramine has no activity against hRXRα, hPPARαγδ, mPXR, hPXR, hLXRα, hTRβ, hRARβ, mCAR, mERRγ, and hVDR receptors .
1
Luteolin 7-diglucuronide
Luteolin 7-diglucuronide
0 Images
1 Cited Publications
Cat. No.: HY-N7269
CAS No.: 96400-45-2
Category:  

other families Flavonoids Flavones Phenols Polyphenols Plants Disease Research Fields Inflammation/Immunology

Target:  

Phosphatase AMPK

Luteolin 7-diglucuronide is the major flavonoid isolated from Aloysia triphylla and Verbena officinalis .
(Rac)-Idroxioleic acid
(Rac)-Idroxioleic acid
0 Images
Cat. No.: HY-129467
CAS No.: 56472-29-8
Purity:  ≥98.0%
Synonyms: 2-Hydroxyoleic acid; 2-OHOA; LAM561
Target:  

Apoptosis

연구분야:  

Cancer

(Rac)-Idroxioleic acid (2-Hydroxyoleic acid) is a synthetic oleic acid (OA) derivative that binds to the plasma membrane and alters lipid organization. (Rac)-Idroxioleic acid has anti-tumor effect .
306-N16B
306-N16B
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Cat. No.: HY-150229
CAS No.: 2803699-70-7
Purity:  98.84%
306-N16B is a selective lung-targeted lipid nanoparticle that reversibly targets lung endothelial cells and specific immune cells through selective adsorption of a protein corona mediated by differences in tail structure (such as fibrinogen β/γ chain). 306-N16B binds to specific plasma proteins in the blood to form a protein corona, which guides the particles to be enriched in the lungs, releases mRNA and promotes target cell gene expression, exerts efficient lung cell transfection activity, and can precisely regulate gene delivery of different cell types in the lungs (such as endothelial cells and macrophages). 306-N16B can be used in gene therapy technologies for hereditary lung diseases including pulmonary lymphangioleiomyomatosis (LAM), restoring tumor suppressor function by delivering Tsc2 mRNA, and can also be used for lung-specific mRNA vaccines and gene editing therapies .
Ilexgenin A
Ilexgenin A
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Cat. No.: HY-N6255
CAS No.: 108524-94-3
Category:  

Aquifoliaceae Triterpenes Terpenoids Periploca aphylla Decne. Plants Disease Research Fields Inflammation/Immunology Cancer

Target:  

TNF Receptor

Ilexgenin A is a pentacyclic triterpenoid, which extracted from Ilex hainanensis Merr. Ilexgenin A can be used for the research of inflammation and cancer .
3,5,7,8,3′,4′-Hexamethoxyflavone
3,5,7,8,3′,4′-Hexamethoxyflavone
0 Images
Cat. No.: HY-N11166
CAS No.: 7741-47-1
Category:  

Melicope triphylla (Lam.) Merr. Flavonoids Flavones Rutaceae Plants

Target:  

Others

3,5,7,8,3′,4′-Hexamethoxyflavone is a flavonoid. 3,5,7,8,3′,4′-Hexamethoxyflavone can be isolated from the leaves of Melicope triphylla MERR .
Niazimicin
Niazimicin
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Cat. No.: HY-N8503
CAS No.: 147821-49-6
Category:  

Alkaloids Other Alkaloids Moringa oleifera Lam. Moringaceae Plants

Target:  

Others

Niazimicin can be isolated from seeds and leaves of Moringa oleifera Lam. Niazimicin is thiocarbamate compound .
Methyl 3-hydroxyoctanoate
Methyl 3-hydroxyoctanoate
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Cat. No.: HY-117201
CAS No.: 7367-87-5
Synonyms: 3-Hydroxy octanoic acid methyl ester
Target:  

Biochemical Assay Reagents

연구분야:  

Others

Methyl 3-hydroxyoctanoate (3-Hydroxy octanoic acid methyl ester) is an ester. Methyl 3-hydroxyoctanoate can be isolated from Pineapple .
Ilexhainanoside D
Ilexhainanoside D
0 Images
Cat. No.: HY-N5040
CAS No.: 1137648-52-2
Category:  

Aquifoliaceae Triterpenes Terpenoids Plants Disease Research Fields Inflammation/Immunology Tabernaemontana elegans Stapf

Target:  

Others

Ilexhainanoside D is the main triterpenoid saponin extracted from Ilex hainanensis Merr., and the combination of Ilexhainanoside D and ilexsaponin A1 has anti-inflammation effect .
Bruceine E
Bruceine E
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Cat. No.: HY-N3015
CAS No.: 21586-90-3
Category:  

Simaroubaceae Terpenoids Metabolic Disease Diterpenoids Plants Disease Research Fields Brucea javanica (L.) Merr.

Target:  

Others

Bruceine E is a quassinoid from seeds of Brucea javanica (L.) Merr, exhibiting hypoglycemia effect . Bruceine E exhibits blood glucose lowering effect in both nondiabetic mice and Streptozotocin (STZ (HY-13753))-induced diabetic rats at lower dose .
Luteolin 7-diglucuronide (Standard)
Luteolin 7-diglucuronide (Standard)
0 Images
Cat. No.: HY-N7269R
CAS No.: 96400-45-2
Category:  

other families Flavonoids Flavones Phenols Polyphenols Plants

Target:  

Reference Standards Phosphatase AMPK

Luteolin 7-diglucuronide (Standard) is the analytical standard of Luteolin 7-diglucuronide. This product is intended for research and analytical applications. Luteolin 7-diglucuronide is the major flavonoid isolated from Aloysia triphylla and Verbena officinalis .
6-Formyllimetin
6-Formyllimetin
0 Images
Cat. No.: HY-N10842
CAS No.: 88140-31-2
Category:  

Centella asiatica (L.) Urb. Coumarins Phenylpropanoids Plants Umbelliferae

Target:  

Others

6-Formyllimetin is a natural product isolated from the root bark of T. asiatica LAM .
(+)-6-(3-Chloro-2-hydroxy-3-methylbutyl)-5,7-dimethoxycoumarin
(+)-6-(3-Chloro-2-hydroxy-3-methylbutyl)-5,7-dimethoxycoumarin
0 Images
Cat. No.: HY-N10803
CAS No.: 15575-50-5
Category:  

Cucurbitaceae Centella asiatica (L.) Urb. Coumarins Phenylpropanoids Plants Umbelliferae Momordica charantia Linn.

Target:  

Others

(+)-6-(3-Chloro-2-hydroxy-3-methylbutyl)-5,7-dimethoxycoumarin is a nature product that could be isolated form the root bark of Toddalia asiatica (L.) LAM .
5-InoAz
5-InoAz
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Cat. No.: HY-164915
CAS No.: 1218932-97-8
Target:  

Bacterial

연구분야:  

Metabolic Disease

5-InoAz is an inositol analogue used as a metabolic probe for labeling the mycobacterial cell envelope. 5-InoAz integrates into cell envelope glycolipids [phosphatidylinositol mannoside (PIM), PIM-anchored lipomannan (LM), and lipoarabinomannan (LAM)] .
Niazirin
Niazirin
0 Images
Cat. No.: HY-N9097
CAS No.: 122001-32-5
Category:  

Moringa oleifera Lam. Moringaceae Plants Saccharides Monosaccharides

Target:  

Reactive Oxygen Species (ROS) SOD Glutathione Peroxidase PKC NADPH Oxidase

Niazirin is an orally active antioxidant. Niazirin can be isolated from Moringa oleifera Lam. Niazirin reduces the production levels of ROS and MDA, while increasing the levels of superoxide dismutase SOD and glutathione peroxidase GPx. Niazirin also abolishes high glucose-induced PKCζ activation and inhibits Nox4 protein expression. Niazirin exhibits excellent free radical scavenging activity. Niazirin significantly inhibits high glucose-induced proliferation of vascular smooth muscle cells. Niazirin can be used in the research of diabetic atherosclerosis .
Ulopterol
Ulopterol
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Cat. No.: HY-N0080
CAS No.: 28095-18-3
Synonyms: Peucedanol methyl ether
Category:  

Infection Toddalia asiatica (L.) Lam. Rutaceae Coumarins Phenylpropanoids Plants Disease Research Fields

Target:  

Bacterial Fungal

Ulopterol is a coumarin isolated from the leaves of Toddalia asiatica (L.) Lam with potent antibacterial and antifungal activities .
Tinophyllol
Tinophyllol
0 Images
Cat. No.: HY-N10482
CAS No.: 96552-83-9
Category:  

Terpenoids Diterpenoids Plants Menispermaceae Arcangelisia flava (L.) Merr.

Target:  

Fungal

Tinophyllol, a furanoditerpenoid, is a natural product found in Arcangelisia flava MERR. Tinophyllol has good activity against Botrytis cinerea .
Apilimod hydrochloride
Apilimod hydrochloride
0 Images
Cat. No.: HY-14644B
CAS No.: 870087-37-9
Synonyms: STA 5326 hydrochloride; LAM-002A free base hydrochloride; AIT-101 hydrochloride
Target:  

NOD-like Receptor (NLR)

연구분야:  

Infection Inflammation/Immunology

Apilimod (STA 5326) hydrochloride is a PIKFYVE kinase inhibitor that promotes NLRP3 inflammatory vesicle activation and IL-1β secretion. Apilimod hydrochloride has been shown to inhibit host cell proteases, which may prevent viral invasion but also block antiviral immune responses, potentially exacerbating immunosuppression in COVID-19.
Assay Types